Idler compounds

We’ve created the Todd Idler Compound Library to catalogue, share and make best use of compounds synthesised in the Todd Group. The setup and sharing process is summarised in the graphic below and described in the manuscript “Idler Compounds: A Simple Protocol for Openly Sharing Fridge Contents for Cross-Screening” (ChemRxiv DOI pending).

As proof-of-concept, compounds have been shared with UKHSA, generating new data that now feeds into ongoing programmes and offers new starting points for projects. Results and underlying data are openly provided via the resources below.

Get started (Resources)

• Live inventory (Google Sheet): Link to spreadsheet

• LabArchives notebook (data): View notebook

• Zenodo collection: https://zenodo.org/records/16793669

How it works

1. Accumulate compounds (purchased & synthesised).
2. Build a shareable library (stock samples + online records).
3. Curate a diverse plate and share (e.g., with UKHSA).
4. Receive results → generate new data & starting points → feed back to projects.

Library composition properties & Screening overview and highlighted compounds

All Data (2025)

All_Data_MHT_0001.xlsx

For collaborators

Interested in using or contributing to the Idler library? Please get in touch with the Todd Group (matthew.todd@ucl.ac.uk).

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Last updated: Aug 2025